Request PDF on ResearchGate | Dermatitis granulomatosa intersticial con artritis | —Interstitial granulomatous dermatitis with arthritis is a systemic disease. La dermatitis granulomatosa intersticial con artritis es una enfermedad sistémica que afecta a la piel y al sistema musculosquelético. Esta nueva entidad se. Summary. An Orphanet summary for this disease is currently under development. However, other data related to the disease are accessible from the Additional.

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Myelodysplastic syndrome presenting as generalized granulomatous dermatitis. Our patient showed decreased levels of free thyroxine and high titers of anti-thyroid antibodies, disclosing a previously unrecognized autoimmune thyroiditis. Accentuation of the process in the reticular dermis is a characteristic feature, although abnormalities can involve the full thickness of the dermis or the superficial hypodermis.

Clin Rheumatol Interstitial granulomatous dermatitis with arthritis. The lack of randomized clinical studies has prevented an optimal treatment for IGD to dernatitis determined. CASE REPORT A year-old Caucasian female presented to the emergency room with 2 erythematous, sharply demarcated, painful, indurated plaques, on her left arm and right thigh, which had appeared in the previous 48 hours.

Relapsing intersticail, interstitial granulomatous dermatitis and antiphospholipid syndrome: The clinical case report of a year-old diabetic teenager with undifferentiated juvenile arthritis and 2- years history of skin-colored maculae and plaques is presented. Sayah A, English JC. Classically it presents itself as linear subcutaneous cords, known as rope sign. Normalization of thyroid function and high-potency topical corticosteroids provided only transitory improvement of the dermatosis.

Please review our privacy policy. Journal List An Bras Dermatol v. Intrrsticial, the growing number of reports linking it to a variety of autoimmune disorders, namely rheumatoid arthritis, systemic lupus erythematosus and Churg-Strauss syndrome, strongly support the hypothesis of an underlying autoimmune process.


Dermatitis; Granulomatous disease, chronic; Thyroiditis; Thyroiditis, autoimmune.

Intersticiak treatments have included:. Interstitial granulomatous dermatitis secondary to acute promyelocytic leukemia. National Center for Biotechnology InformationU. The characteristic histological features of interstitial granulomatous drug reaction are:.

There are some reports of association of malignancy with interstitial granulomatous dermatitis. Only comments seeking to improve the quality and accuracy of information on the Orphanet website are accepted. Article in xml format Article references How to cite this article Automatic translation Send this article by e-mail.

To improve our services and products, we use “cookies” own or third parties authorized to show advertising related to client preferences through the analyses of navigation customer behavior. Although the original manifestation had been described as subcutaneous linear nodules, also known as rope sign 1later reports showed a clinical spectrum quite heterogeneous which vary from hyperpigmented, erythematous papules, subcutaneous plaques, annular lesions to firm red-purplish nodules as observed in our patient.

This item has received. Gramulomatosa granulomatous dermatitis is a histologic inflammatory reaction, with variable cutaneous expression. Services on Demand Journal.

Interstitial granulomatous dermatitis with plaques and arthritis is an idiopathic rare disease that usually affects young women. The documents contained in this web site are presented for information purposes only. It presents as annular plaques on the arms, medial thighs and skin folds. Subscribe to our Newsletter.

Only comments written in English can be processed. Altough the original description reported subcutaneous indurated linear cords “the rope sign” along the lateral aspect of the trunk, the clinical picture is now known to be quite heterogeneous, as granulomatpsa may also manifest as patches, papules, nodules or plaques, and at different body sites.


Dermatitis granulomatosa intersticial con artritis | Actas Dermo-Sifiliográficas (English Edition)

Autoimmune thyroiditis has already been mentioned once in association with IGD. DermNet NZ does not provide an online consultation service.

Histologically, grznulomatosa diffuse interstitial infiltrate with histiocytes and foci of collagen degeneration is seen, as well as the formation of small granulomas around these areas of degeneration. Granuloma annulare and interstitial granulomatous dermatitis may appear similar clinically and histologically. Its physiopathology is uncertain, however the association with autoimmune diseases and vasculitides suggests a mechanism mediated by immunocomplexes.

Medications that have been reported to be implicated in interstitial granulomatous drug eruption include:. Self-skin examination New smartphone apps to check your skin Learn more Sponsored content. Pemphigus Vegetans in the Inguinal Folds.

In conclusion, IGD is an uncommon skin disease that may be secondary to an underlying systemic condition. If you have any concerns with your skin or its treatment, see a dermatologist for advice.

The granulomatous reaction pattern.

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Dubey S, Merry P. Granuloma annulare also presents with papules and plaques but these are typically on the back of the hands or feet, whereas the trunk is a more common site for interstitial granulomatous dermatitis. Dense inflammatory infiltrate in interstitial thickened collagen. Interstitial granulomatous dermatitis associated with the use of tumor necrosis factor gtanulomatosa inhibitors.